Notably, there is a significant correlation between plasma Gln concentrations and GSH levels
G6PD deficiency was the first prevalent enzyme deficiency characterized by the World Health Organization in 1984 (3)
Moreover, we excluded patients and controls who suffered from neurodegenerative and neuroinflammatory disorders, such as chronic fatigue syndrome [54], Parkinsons or Alzheimers disease, multiple sclerosis, stroke, or systemic (auto)immune diseases such as diabetes mellitus, psoriasis, rheumatoid arthritis, inflammatory bowel disease and scleroderma, and liver and renal disease
This absence of negative interactions supports the safety of combination approaches
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