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In general, taking higher-than-recommended levels of vitamin B12 is well tolerated
Tracking progress systematically identifies when dose modifications might help and when other factors need attention
Paraesthesia, balance problems, or cognitive difficulties may persist despite normalising blood counts
First, a bacterial reverse mutation test (Ames test) assessed AOD9604s mutagenic potential using four histidine-dependent auxotrophic mutants of Salmonella typhimurium (TA1535, TA1537, TA98, TA100) and one tryptophan-dependent auxotrophic mutant of Escherichia coli (WP2 uvrA), using both plate incorporation and pre-incubation methods at doses of 0, 1.6, 8, 40, 200, 1,000, and 2,000 g AOD9604/plate
[6] [7] Do not freeze biotin injection and avoid storing it in very hot places (such as in direct sunlight or a car glovebox on a hot day) as extreme temperatures can reduce potency
