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Despite the central role of myocardial fibrosis in the pathology of HFpEF, there are currently no evidence-based therapies that specifically target this process 52,96
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www.sciencedirect.com Nrf2 (nuclear factor erythroid 2-related factor 2) is a cellular protein that regulates the expression of antioxidant and stress response proteins
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Glucagon-like peptide-1 (GLP-1) is a naturally occurring incretin hormone primarily produced by L-cells in the small intestine, playing a major role in regulating blood sugar levels, appetite, and overall metabolic health
SOC=standard of care
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