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Monitor levels every 6 months given high-risk status
There is always a focus on safety and sterility more than anything else
Opened vials: refrigeration at 2-8C is recommended
If a vial is smaller than the intended diluent volume, the reconstitution plan is wrong before it starts
With the development of ADC approach, PBD has been used as a payload associated with specific antibodies in the treatment of different diseases, limiting the high toxicity associated with this molecule
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