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Even after approval, the $600 monthly cost for Ozempic was too high, so her doctor suggested compounded semaglutide as a more affordable alternative

Overall, the paper suggests that the effect of GLP-1-based drugs on muscle appears to be comparable to that of natural weight loss except for the different molecular signature, which may have yet undiscovered long-term effects

Novo Nordisk is also looking to extend the indications for semaglutide even further, with trials on the go in metabolic dysfunction-associated steatohepatitis (MASH) and Alzheimer's disease.

There is also a risk of worsening diabetic retinopathy with rapid improvement in blood glucose control