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Series A, Biological Sciences and Medical Sciences

Recovery: Most patients experience mild swelling and bruising for a few days

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Authored by: Sergey Terushkin, MD, FACS, FASMBS, DABOM, DABS-FPMBS Key Takeaways Average Timeline: Clinical trials show losing 50 lbs on tirzepatide takes about 72 weeks, with higher doses delivering greater results

So, if someone with the characteristics of this treatment group takes semaglutide 2.4mg on the standard 16 week titration schedule, they can expect a (geometric) average reduction of 48.6% The way the researchers are interpreting their findings is that the average reduction in uACR is -48.6% BUT if the placebo group is a correct representation of doing nothing (and they did nothing) they could have expected their uACR to go up 7.4% over those same 24 weeks, so in theory they end up 52.1% better off based on the geometric mean