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Active site residues C46 (oxidized), L48, Q81, and W136 are highlighted and shown as sticks
Acute toxicity studies in animals, if extrapolated to humans, implicate a single dose of 10-15 grams necessary to produce significant liver toxicity, although several human case reports have shown toxicity at doses less than 4 grams per day (likely due to having one or more risk factors for sensitivity to toxicity) (Amar 2007)
Cosmetics 2(3):259276 Gautier A, Juillerat A, Heinis C, Corra IR Jr, Kindermann M, Beaufils F, Johnsson K (2008) An engineered protein tag for multiprotein labeling in living cells
timolol, careolol), and topical steroids to reduce inflammation induced nerve damage (Anthony N, 2021)
GREEN TEA (AND EGCG) In addition to containing small amounts of caffeine, green tea is rich in catechins with multiple benefits, promoting fat loss through catecholamine activation and AMPK stimulation
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