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An enzyme called tyrosinase is needed to create melanin (the pigment that causes the brown spots) and while several other skin lightening agents work to inhibit the synthesis of tyrosinase itself (like vitamin C or licorice), arbutin lets tyrosinase be and rather hinders the melanin-forming activity of the enzyme

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Although previous studies have shown L-carnitine to have cardioprotective effects [47], recent studies have also shown that derivatives of L-carnitine may have adverse consequences on cardiovacular health

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If you work in a high-stress environment, travel frequently, or are exposed to secondhand smoke or heavy pollution, your body uses up its glutathione stores more quickly