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IGF-1 LR3 and the Future of Regenerative Medicine Ongoing studies are evaluating IGF-1 LR3 for: Neuroprotection after ischemic injury Cardiac repair post-myocardial infarction (inspired by MGFs cardiac benefits) Accelerating tendon and ligament healing in sports medicine 12
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Drug effects in lean mice Single peripheral bolus administration (10 nmol kg 1 ) of GLP-1GIP and GLP-1GIPLani both induced conditioned taste avoidance (CTA) in lean wild-type mice, with GLP-1GIPLani having a slightly greater effect compared with GLP-1GIP, and without inducing CTA in glutamatergic ( Vglut2-cre ) Glp1r -knockout mice ( Vglut2 is also known as Slc17a6
Without protein-sparing measures, studies suggest 2040% of total weight lost on GLP-1 therapy can be lean mass
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