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Gln depletion therapy can inhibit Gln metabolism in tumor cells, but in colon cancer, it has been observed that Gln depletion promotes the expression of the aspartate/glutamate transporter SLC1A3 in tumor cells, increasing the intracellular glutamate concentration and promotes Gln synthesis
2013 Jun 10;184:1-5
Inconsistent dosing or improper storage (temperature excursions above 8C) delays or eliminates the response entirely
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and [5] promotion of neovascularization, which entails the induction of neovascular network formation through increased secretion of endothelial cells and pro-angiogenic factors, thus accelerating the healing process of damaged skin [127, 128]
